Troponin I is a regulatory protein part of the troponin com- plex which plays a vital part in non smooth muscle contrac- tion (skeletal and cardiac).
The cardiac isoform of troponin-I (cTnI) is only expressed in cardiac muscle. Cardiac Troponin I is principally trapped within cardiac muscle cells (although minute amount of tro- ponin is present in the blood stream in regular healthy state) and the leakage (release) of high amounts of cardiac tro- ponin in the blood stream indicates cardiac injury.
Elavated cTnI levels are now widley considered as the stand- ard biochemical marker for the diagnosis of myocardial in- farction (commonly known as heart attack), a deadly med- ical emergency charachtrized by heart muscle cells death due to loss of oxygen reaching the heart.
The release of Tropinin I into the blood stream starts 4-6 hours after cardiac injury and remains high for up to 2 weeks thus providing for a long window of detection for cardiac injury as well as monitering already exisiting heart conditions.
Turklab’s Troponin I Test is a immunochromatographic test for the qualitative detection of human cardiac marker Troponin I (cTnI) in human whole blood / serum / plasma to aid diagnosis of myocardial infarction (MI).
• Wide range of samples can be used, plasma, serum, cap- illary blood, or venous blood.
• Verified non-reactivity with skletal Troponin I, Troponin T and cardiac myosin.
• Sensitivity: 99,4%
• Specificity: 99,9%