Kalite
Calprotectin is a protein that plays an important role in the body's immune response, especially in defense against inflammation and microbial infections, and is produced by neutrophils and other immune cells. Calprotectin is released into the intestinal lumen through various mechanisms such as leukocyte shedding, active secretion, cell disruption and cell death. The level of calprotectin released during inflammatory processes can be measured in various body fluids, most commonly in fecal samples. The determination of calprotectin in fecal samples has become an important diagnostic marker, especially in gastrointestinal disorders such as Crohn's disease and ulcerative colitis, due to its resistance to enzymatic degradation.
INTENDED USE
The Calprotectin Test is a rapid chromatographic immunoassay for the qualitative detection of Calprotectin in human feces specimen which might be useful for the diagnosis of inflammatory gastrointestinal disorders.
PERFORMANCE EVALUATION
Sensitivity: 98.53%
Specificity: 99.51%
Accuracy: 98.58%
*95% Confidence Intervals